2 edition of evaluation of the 1954 poliomyelitis vaccine trials found in the catalog.
evaluation of the 1954 poliomyelitis vaccine trials
University of Michigan. Poliomyelitis Vaccine Evaluation Center.
in Ann Arbor, Mich
Written in English
|LC Classifications||RC180.6 .M5|
|The Physical Object|
|Pagination||xiv, 50, 63 p.|
|Number of Pages||63|
|LC Control Number||55062679|
Polio vaccines are vaccines used to prevent poliomyelitis (polio). Two types are used: an inactivated poliovirus given by injection (IPV) and a weakened poliovirus given by mouth (OPV). The World Health Organization (WHO) recommends all children be fully vaccinated against polio. The two vaccines have eliminated polio from most of the world, and reduced the number of cases reported each year. The year marks the ”ftieth anniversary of the celebrated Salk polio vaccine trial. This enormous clinical trial, involving million children, was carried out with the co-operation and assistance of hundreds of thousands of lay volunteers, along with medical professionals and local health departments throughout the USA.
Vaccine Trial Regulation Errors. Poliomyelitis, a viral disease, has the potential to damage the central nervous system and leave children paralyzed. Jonas Salk developed an inactivated vaccine to combat the rising prevalence of the disease around the world. In the results from the preliminary trial of Salk’s vaccine were announced to the general public and within 2 hours it was licensed. Unfortunately, this book can't be printed from the OpenBook. If you need to print pages from this book, we recommend downloading it as a PDF. Visit to get more information about this book, to buy it in print, or to download it as a free PDF.
History(of(Vaccines(Polio(Timeline(Bibliography!!©TheCollegeofPhysiciansofPhiladelphia! page!1! SourcesforHistoryofVaccinesPolioTimeline(Alexander!ER.!Landmark. Equally remarkable, the Salk polio vaccine trial stands as the largest peacetime mobilization of volunteers in American history, requiring the efforts of , doctors, nurses, educators and private citizens -- with no money from federal grants or pharmaceutical companies.
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Download Citation | Evaluation of Field Trials of Poliomyelitis Vaccine | This is a section of the book The Challenge of Epidemiology: Issues and Selected Readings.
Edited by four eminent. Get this from a library. An evaluation of the poliomyelitis vaccine trials; summary report. [University of Michigan.
Poliomyelitis Vaccine Evaluation Center.]. On Apthe Salk polio vaccine field trials, involving million children, begin at the Franklin Sherman Elementary School in McLean, Virginia. Am J Public Health Nations Health. May;45(5 Pt 2) An evaluation of the poliomyelitis vaccine trials.
FRANCIS T Jr, KORNS RF, VOIGHT RB, BOISEN M, HEMPHILL FM, NAPIER JA, TOLCHINSKY by: University of Michigan. Poliomyelitis Vaccine Evaluation Center.
Evaluation of the field trial of poliomyelitis vaccine. Ann Arbor, (OCoLC) Document Type: Book: All Authors / Contributors: Thomas Francis, Jr.; University of Michigan.
Poliomyelitis Vaccine Evaluation Center. The purpose of the poliomyelitis vaccine evaluation program in the field trial of was to seek a measure of the prophylactic effect of the preparations of vaccine to be used, the only. * An invited review article on Evaluation of Field Trial of Poliomyelitis Vaccine: Summary Report.
Poliomyelitis Vaccine Evaluation Center. University of Michigan, Ann Arbor, Michigan. April 1. Journal article: An Evaluation of thePoliomyelitis Vaccine Trials.
Vol No.5, Pt. 2 + 51 + 63 pp. Abstract: In this report, the results are given of the trial of an inactivated poliomyelitis poliomyelitis Subject Category: Diseases, Disorders, and Symptoms.
The vaccine was tested in massive field trials, beginning inthat involved million schoolchildren known as "polio pioneers," (seen. The purpose of the poliomyelitis vaccine evaluation program in the field trial of was to seek a measure of the prophylactic effect of the preparations of vaccine to be used, the only assumptions 'being that the experimental background was sound and that the vaccine was to be antigenic and noninfectious.
Email your librarian or administrator to recommend adding this book to your organisation's collection. Essential Epidemiology. 3rd edition An evaluation of the poliomyelitis vaccine trials: summary report. American Journal of Public An evaluation of the poliomyelitis vaccine trials: summary report.
American Journal of Public. FRANCIS T, Jr, KORNS RF, VOIGHT RB, BOISEN M, HEMPHILL FM, NAPIER JA, TOLCHINSKY E. An evaluation of the poliomyelitis vaccine trials.
Am J Public Health Nations Health. May; 45 (5 Pt 2):1– [PMC free article] BODIAN D. Experimental studies on passive immunization against poliomyelitis. The trial was blinded, meaning that the children didn’t know whether they received the vaccine or a saline placebo injection.
Regardless, most viewed themselves if not exactly as test subjects (which they certainly were) but as Polio Pioneers, as they and their parents were encouraged to. The polio vaccine field trials ofsponsored by the National Foundation for Infantile Paralysis (March of Dimes), are among the largest and most publicised clinical trials ever undertaken.
Across the United States, schoolchildren were injected with vaccine or placebo, and more than a million others participated as “observed” controls. THE LARGEST and most expensive medical experiment in history was carried out in Well over a million young children participated, and the immediate direct costs were over 5 million dollars.
The experiment was carried out to assess the effectiveness, if any, of the Salk vaccine as a protection against paralysis or death from poliomyelitis. The study was elaborate in many respects, most.
"Statistics of the Polio Vaccine Trials." journal of the American Statistical Association 50(), 2. Thomas Francis, Jr., et al.
"An Evaluation of the Poliomyelitis Vaccine Trials--Sumnmary Report." American Journal of Public Health 45(5), 3. Paul Meier. "Safety Testing of Poliomyelitis Vaccine.". “No single event impressed me more than what happened on Apthe day the results of the evaluation of the poliomyelitis vaccine field trials were announced.
As I was making my rounds that afternoon, I was taken aback to find a banner stuck on the doors of the respirator wards that read: ‘POLIO VACCINE WORKS.’ The patients had asked the volunteers, who published. THE SALK POLIOMYELITIS VACCINE FIELD TRIAL.
Harry M Marks. Institute of the History of Medicine. The Johns Hopkins University. Baltimore, MD. to appear in. Landmark Clinical Trials. Steven N Goodman, Harry M Marks, Karen Robinson, eds (John Wiley and Sons, forthcoming) c. Polio Vaccine Trial Announcement "Safe, effective, and potent." With these words on ApDr.
Thomas Francis Jr., director of the Poliomyelitis Vaccine Evaluation Center at the University of Michigan School of Public Health, announced to the world that the Salk polio vaccine was up to 90% effective in preventing paralytic polio.
Differences in diagnostic criteria for non-paralytic and paralytic cases introduced as a result of the killed polio-vaccine trial are thought to be the major cause of the fall in incidence of reported poliomyelitis m [Most analyses of killed poliovaceine effectiveness allowing for these factors have showed it to be at least 80%.
Evaluation of the Field Trial of Poliomyelitis Vaccine Final Report, page bound volume from the University of Michigan, Folder 24 Diagnosis and Treatment of the Acute Phase of Poliomyelitis and its Complications, edited by Albert G.
Bower page text, The Cutter incident. On Apfollowing the announcement of the success of the polio vaccine trial, Cutter Laboratories became one of several companies that was recommended to be given a license by the United States government to produce Salk's polio anticipation of the demand for vaccine, the companies had already produced stocks of the vaccine and these were issued once.Thomas Francis, Jr., MD Born: J Died: October 1, Major Contribution: As director of the Poliomyelitis Vaccine Evaluation Center at the University of Michigan, Ann Arbor, Dr.
Francis designed, supervised and evaluated the field trials of the injected inactivated polio vaccine () developed by Jonas Salk.